Use your personal model in ChatGPT, Claude, and Codex

Connect

ChatGPT on the web: on a Plus, Pro, Business, Enterprise, or Education account, turn on Developer mode under Settings → Security and login. Then open Plugins, select +, and create a developer-mode app named Genome Computer using the MCP URL below. In a new conversation, choose Developer mode from the + menu and select Genome Computer.

Claude: open Customize → Connectors, select +, then Add custom connector and enter the same URL. Connect Genome Computer, then enable it for a conversation with + → Connectors. Custom connectors are available on Free (one custom connector), Pro, Max, Team, and Enterprise; a Team or Enterprise owner must add it for the organisation first.

https://mcp.genome.computer/mcp

claude mcp add --transport http genomeComputer https://mcp.genome.computer/mcp
# In Claude Code, run /mcp and choose genomeComputer to authenticate.
/mcp

codex mcp add genomeComputer --url https://mcp.genome.computer/mcp
codex mcp list

The first protected tool call opens the Genome Computer OAuth flow. Sign in to your Portal account, choose one of the genomes explicitly attached to that account as the default, and approve access. Portal accounts and genome access are currently set up in Mission Control.

Already connected? In ChatGPT, refresh Genome Computer from its app details, then disconnect and reconnect its authorisation. In Claude, remove the old custom connector, add it again, and reconnect. This loads the two profile readers and lets you approve read-only profile access. Older permissions do not grant this access.

Try asking

• What information and limitations are available in my personal profile?
• Help me design a work rhythm that fits both my tendencies and what matters to me.
• Help me build a learning routine that fits me.
• Suggest a manageable approach to a creative project that fits me.
• What is still unknown, and is there one question that would make this answer more personal?

Privacy boundary

The connection reads your personal profile through get_personal_model and get_biological_profile with profile:read permission. Retrieved profile topics and sections are shared with the connected app. They can contain genetically derived biological interpretations and sensitive information. It cannot read saved lived context, raw genetic calls or clinical reports, or change your profile or save conversation information. You can revoke OAuth access in your account settings.